Karyopharm Therapeutics Inc. Logo

Karyopharm Therapeutics Inc.

KPTI

(1.8)
Stock Price

0,64 USD

-42.02% ROA

58.62% ROE

-1.13x PER

Market Cap.

105.108.612,00 USD

-147.33% DER

0% Yield

-58.93% NPM

Karyopharm Therapeutics Inc. Stock Analysis

Karyopharm Therapeutics Inc. Fundamental Analysis

Fundamental analysis in stock investing is like studying the foundation of a house before buying it. It involves looking at a company's financial health, like its earnings, assets, and debts, to determine if it's a good investment based on its fundamental strength and potential for growth.

Karyopharm Therapeutics Inc. Fundamental Stock Analysis
# Analysis Rating
1 ROE

The stock's ROE exceeds expectations (239.46%), revealing strong profitability and efficient use of shareholders' equity, making it an attractive investment opportunity.

2 PBV

The stock's low PBV ratio (-0.89x) suggests it's undervalued, making it an attractive opportunity for investors.

3 DER

The stock has a low debt to equity ratio (-173%), which means it has a small amount of debt compared to the ownership it holds

4 Graham Number

Based on the Graham number, this company's stock price appears to be lower than its intrinsic value, signaling a potentially favorable investment choice.

5 ROA

The stock's ROA (-51.77%) suggests that it's struggling to generate profits from its assets, making it a risky choice for investment.

6 Revenue Growth

Company's revenue has stayed stagnant, showing no signs of improvement and making it a less favorable choice.

7 Net Profit Growth

This company's net profit has remained stagnant over the past five years, indicating a lack of growth and making it a less favorable investment option.

8 Assets Growth

Company's revenue has remained stagnant over the past three years, indicating a lack of growth and making it a less favorable option.

9 Dividend Growth

The company's dividend growth has been flat for the past three years, raising concerns for potential investors seeking reliable returns.

10 Dividend

Investors should note the absence of dividends from the company in the last three years, indicating potential financial challenges.

11 Buffet Intrinsic Value

The company's stock presents a potential concern as it appears overvalued (-1) by Warren Buffett's formula, indicating that its market price exceeds its estimated intrinsic value.

Karyopharm Therapeutics Inc. Technical Analysis

Technical analysis in stock investing is like reading the patterns on a weather map to predict future weather conditions. It involves studying past stock price movements and trading volumes to make predictions about where a stock's price might go next, without necessarily looking at the company's financial health.

Karyopharm Therapeutics Inc. Technical Stock Analysis
# Analysis Recommendation
1 Awesome Oscillator Hold
2 MACD Buy
3 RSI Hold
4 Stoch RSI Sell

Karyopharm Therapeutics Inc. Price Chart

Financial Statements

Financial statements are like report cards for companies. They show how much money a company makes (income statement), what it owns and owes (balance sheet), and where it spends its money (cash flow statement), helping stock investors understand if a company is healthy and worth investing in.

Income Statements

An income statement for a company is like a scoreboard for its profits and losses. It shows how much money the company made (revenue) and how much it spent to make that money (expenses), helping stock investors see if a company is making a profit or not.

Revenue in stock investing is the total amount of money a company earns from its sales, and it's a key factor that investors consider to assess a company's financial performance and growth potential.

Karyopharm Therapeutics Inc. Revenue
Year Revenue Growth
2011 152.000
2012 634.000 76.03%
2013 387.000 -63.82%
2014 229.000 -69%
2015 250.000 8.4%
2016 154.000 -62.34%
2017 1.605.000 90.4%
2018 30.336.000 94.71%
2019 40.893.000 25.82%
2020 108.085.000 62.17%
2021 209.819.000 48.49%
2022 157.074.000 -33.58%
2023 144.036.000 -9.05%
2023 146.033.000 1.37%
2024 171.144.000 14.67%

Research and Development Expenses are the costs a company incurs to create and improve its products or services, which can be important for investors to evaluate a company's innovation and potential for future growth.

Karyopharm Therapeutics Inc. Research and Development Expenses
Year Research and Development Expenses Growth
2011 8.623.000
2012 14.095.000 38.82%
2013 28.452.000 50.46%
2014 60.127.000 52.68%
2015 97.744.000 38.49%
2016 86.938.000 -12.43%
2017 107.273.000 18.96%
2018 161.372.000 33.52%
2019 122.340.000 -31.9%
2020 150.813.000 18.88%
2021 160.842.000 6.24%
2022 148.662.000 -8.19%
2023 142.212.000 -4.54%
2023 138.220.000 -2.89%
2024 153.120.000 9.73%

General and Administrative Expenses are the costs a company incurs to run its day-to-day operations, such as office rent, salaries, and utilities, which investors consider to understand a company's overall efficiency and management effectiveness.

Karyopharm Therapeutics Inc. General and Administrative Expenses
Year General and Administrative Expenses Growth
2011 1.840.000
2012 2.429.000 24.25%
2013 5.885.000 58.73%
2014 15.948.000 63.1%
2015 21.582.000 26.11%
2016 23.948.000 9.88%
2017 24.870.000 3.71%
2018 48.847.000 49.09%
2019 0 0%
2020 126.417.000 100%
2021 143.846.000 12.12%
2022 145.401.000 1.07%
2023 0 0%
2023 131.881.000 100%
2024 124.280.000 -6.12%

EBITDA stands for Earnings Before Interest, Taxes, Depreciation, and Amortization. It is a measure that helps stock investors analyze a company's profitability by looking at its earnings without considering certain expenses. This helps to get a clearer picture of the company's financial performance and its ability to generate cash flow.

Karyopharm Therapeutics Inc. EBITDA
Year EBITDA Growth
2011 -10.228.000
2012 -15.766.000 35.13%
2013 -33.950.000 53.56%
2014 -75.776.000 55.2%
2015 -119.076.000 36.36%
2016 -110.732.000 -7.54%
2017 -130.538.000 15.17%
2018 -175.888.000 25.78%
2019 -183.903.000 4.36%
2020 -168.824.000 -8.93%
2021 -97.774.000 -72.67%
2022 -139.926.000 30.12%
2023 -113.684.000 -23.08%
2023 -129.009.999 11.88%
2024 -112.116.000 -15.07%

Gross profit is the money a company makes from selling its products or services after subtracting the cost of producing or providing them, and it is an important measure for investors to understand a company's profitability.

Karyopharm Therapeutics Inc. Gross Profit
Year Gross Profit Growth
2011 152.000
2012 -13.461.000 101.13%
2013 -28.065.000 52.04%
2014 -59.898.000 53.15%
2015 -97.494.000 38.56%
2016 -86.784.000 -12.34%
2017 -105.668.000 17.87%
2018 -131.036.000 19.36%
2019 38.486.000 440.48%
2020 105.380.000 63.48%
2021 206.417.000 48.95%
2022 151.861.000 -35.92%
2023 140.392.000 -8.17%
2023 140.561.000 0.12%
2024 164.920.000 14.77%

Net income in stock investing is like the money a company actually gets to keep as profit after paying all its bills, and it's an important measure to understand how well a company is doing financially.

Karyopharm Therapeutics Inc. Net Profit
Year Net Profit Growth
2011 -10.311.000
2012 -15.888.000 35.1%
2013 -33.947.000 53.2%
2014 -75.777.000 55.2%
2015 -118.181.000 35.88%
2016 -109.577.000 -7.85%
2017 -128.984.000 15.05%
2018 -178.407.000 27.7%
2019 -199.590.000 10.61%
2020 -196.273.000 -1.69%
2021 -124.088.000 -58.17%
2022 -165.291.000 24.93%
2023 -138.024.000 -19.76%
2023 -143.099.000 3.55%
2024 95.168.000 250.36%

EPS, or earnings per share, is a measure that shows how much profit a company has earned for each outstanding share of its stock, and it is important for stock investors as it helps understand the profitability of a company and compare it with other companies in the market.

Karyopharm Therapeutics Inc. Earning per Share (EPS)
Year Earning per Share (EPS) Growth
2011 -10
2012 -7 -66.67%
2013 -6 -20%
2014 -2 -150%
2015 -3 33.33%
2016 -3 -50%
2017 -3 0%
2018 -3 33.33%
2019 -3 0%
2020 -3 -50%
2021 -2 -100%
2022 -2 50%
2023 -1 -100%
2023 -1 0%
2024 1 0%

Cashflow Statements

Cashflow statements show the movement of money in and out of a company, helping stock investors understand how much money a company makes and spends. By examining cashflow statements, investors can assess if a company is generating enough cash to pay its bills, invest in growth, and provide returns to stockholders.

Free cash flow is the leftover cash that a company generates after covering its operating expenses and capital expenditures, which is important for stock investors as it shows how much money a company has available to invest in growth, pay dividends, or reduce debt.

Karyopharm Therapeutics Inc. Free Cashflow
Year Free Cashflow Growth
2011 -8.925.000
2012 -15.630.000 42.9%
2013 -30.347.000 48.5%
2014 -54.281.000 44.09%
2015 -95.445.000 43.13%
2016 -84.461.000 -13%
2017 -73.779.000 -14.48%
2018 -161.480.000 54.31%
2019 -191.028.000 15.47%
2020 -160.379.000 -19.11%
2021 -112.828.000 -42.14%
2022 -149.672.000 24.62%
2023 -92.723.000 -61.42%
2023 1.298.000 7243.53%
2024 -38.498.000 103.37%

Operating cash flow represents the cash generated or consumed by a company's day-to-day operations, excluding external investing or financing activities, and is crucial for stock investors as it shows how much cash a company is generating from its core business operations.

Karyopharm Therapeutics Inc. Operating Cashflow
Year Operating Cashflow Growth
2011 -8.549.000
2012 -15.509.000 44.88%
2013 -30.290.000 48.8%
2014 -51.447.000 41.12%
2015 -94.029.000 45.29%
2016 -84.391.000 -11.42%
2017 -73.717.000 -14.48%
2018 -159.117.000 53.67%
2019 -190.822.000 16.61%
2020 -160.234.000 -19.09%
2021 -107.116.000 -49.59%
2022 -149.554.000 28.38%
2023 -92.723.000 -61.29%
2023 1.298.000 7243.53%
2024 -38.498.000 103.37%

Capex, short for capital expenditures, refers to the money a company spends on acquiring or upgrading tangible assets like buildings, equipment, or technology, which is important for stock investors as it indicates how much a company is investing in its infrastructure to support future growth and profitability.

Karyopharm Therapeutics Inc. Capital Expenditure
Year Capital Expenditure Growth
2011 376.000
2012 121.000 -210.74%
2013 57.000 -112.28%
2014 2.834.000 97.99%
2015 1.416.000 -100.14%
2016 70.000 -1922.86%
2017 62.000 -12.9%
2018 2.363.000 97.38%
2019 206.000 -1047.09%
2020 145.000 -42.07%
2021 5.712.000 97.46%
2022 118.000 -4740.68%
2023 0 0%
2023 0 0%
2024 0 0%

Balance Sheet

Balance sheets provide a snapshot of a company's financial health and its assets (such as cash, inventory, and property) and liabilities (like debts and obligations) at a specific point in time. For stock investors, balance sheets help assess the company's overall worth and evaluate its ability to meet financial obligations and support future growth.

Equity refers to the ownership interest or stake that shareholders have in a company, representing their claim on its assets and earnings after all debts and liabilities are paid.

Karyopharm Therapeutics Inc. Equity
Year Equity Growth
2011 -12.651.000
2012 -27.877.000 54.62%
2013 154.934.000 117.99%
2014 206.794.000 25.08%
2015 198.365.000 -4.25%
2016 162.243.000 -22.26%
2017 129.464.000 -25.32%
2018 183.170.000 29.32%
2019 49.774.000 -268%
2020 50.546.000 1.53%
2021 -79.673.000 163.44%
2022 -16.656.000 -378.34%
2023 -136.206.000 87.77%
2023 -100.396.000 -35.67%
2024 -132.139.999 24.02%

Assets represent the valuable resources that a company owns, such as cash, inventory, property, and equipment, and understanding a company's assets helps investors assess its value and potential for generating future profits.

Karyopharm Therapeutics Inc. Assets
Year Assets Growth
2011 7.224.000
2012 1.311.000 -451.03%
2013 158.226.000 99.17%
2014 220.337.000 28.19%
2015 215.443.000 -2.27%
2016 180.385.000 -19.44%
2017 180.294.000 -0.05%
2018 341.192.000 47.16%
2019 294.963.000 -15.67%
2020 313.050.000 5.78%
2021 305.305.000 -2.54%
2022 358.172.000 14.76%
2023 240.438.000 -48.97%
2023 269.960.000 10.94%
2024 213.977.000 -26.16%

Liabilities refer to the financial obligations or debts that a company owes to creditors or external parties, and understanding a company's liabilities is important for investors as it helps assess the company's financial risk and ability to meet its obligations.

Karyopharm Therapeutics Inc. Liabilities
Year Liabilities Growth
2011 19.875.000
2012 29.188.000 31.91%
2013 3.292.000 -786.63%
2014 13.543.000 75.69%
2015 17.078.000 20.7%
2016 18.142.000 5.86%
2017 50.830.000 64.31%
2018 158.022.000 67.83%
2019 245.189.000 35.55%
2020 262.504.000 6.6%
2021 384.978.000 31.81%
2022 374.828.000 -2.71%
2023 376.644.000 0.48%
2023 370.356.000 -1.7%
2024 346.117.000 -7%

Karyopharm Therapeutics Inc. Financial Ratio (TTM)

Valuation Metrics

Revenue per Share
1.2
Net Income per Share
-0.74
Price to Earning Ratio
-1.13x
Price To Sales Ratio
0.72x
POCF Ratio
-0.78
PFCF Ratio
-0.81
Price to Book Ratio
-0.77
EV to Sales
1.48
EV Over EBITDA
-1.69
EV to Operating CashFlow
-1.66
EV to FreeCashFlow
-1.65
Earnings Yield
-0.88
FreeCashFlow Yield
-1.24
Market Cap
0,11 Bil.
Enterprise Value
0,22 Bil.
Graham Number
4.27
Graham NetNet
-1.35

Income Statement Metrics

Net Income per Share
-0.74
Income Quality
1.45
ROE
0.67
Return On Assets
-0.46
Return On Capital Employed
-0.98
Net Income per EBT
1
EBT Per Ebit
0.69
Ebit per Revenue
-0.85
Effective Tax Rate
-0

Margins

Sales, General, & Administrative to Revenue
0.84
Research & Developement to Revenue
1.02
Stock Based Compensation to Revenue
0.14
Gross Profit Margin
0.96
Operating Profit Margin
-0.85
Pretax Profit Margin
-0.59
Net Profit Margin
-0.59

Dividends

Dividend Yield
0
Dividend Yield %
0
Payout Ratio
0
Dividend Per Share
0

Operating Metrics

Operating Cashflow per Share
-1.08
Free CashFlow per Share
-1.08
Capex to Operating CashFlow
-0
Capex to Revenue
0
Capex to Depreciation
0.59
Return on Invested Capital
-2.1
Return on Tangible Assets
-0.42
Days Sales Outstanding
95.2
Days Payables Outstanding
169.42
Days of Inventory on Hand
210.54
Receivables Turnover
3.83
Payables Turnover
2.15
Inventory Turnover
1.73
Capex per Share
0

Balance Sheet

Cash per Share
1,26
Book Value per Share
-1,09
Tangible Book Value per Share
-1.09
Shareholders Equity per Share
-1.09
Interest Debt per Share
1.83
Debt to Equity
-1.47
Debt to Assets
0.91
Net Debt to EBITDA
-0.87
Current Ratio
3.62
Tangible Asset Value
-0,13 Bil.
Net Current Asset Value
-0,14 Bil.
Invested Capital
154720000
Working Capital
0,15 Bil.
Intangibles to Total Assets
0
Average Receivables
0,03 Bil.
Average Payables
0,00 Bil.
Average Inventory
3122500
Debt to Market Cap
1.85

Dividends

Dividends in stock investing are like rewards that companies give to their shareholders. They are a portion of the company's profits distributed to investors, typically in the form of cash payments, as a way for them to share in the company's success.

Karyopharm Therapeutics Inc. Dividends
Year Dividends Growth

Karyopharm Therapeutics Inc. Profile

About Karyopharm Therapeutics Inc.

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases. The company discovers, develops, and commercializes novel and Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1. Its lead compound, include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma, and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company has license agreement with Menarini Group to develop and commercialize NEXPOVIO for human oncology indications in Europe, including the United Kingdom; Latin America; and other countries. Its oral SINE compounds also designed to force nuclear accumulation in the levels of multiple tumor suppressor and growth regulatory proteins. The company was incorporated in 2008 and is headquartered in Newton, Massachusetts.

CEO
Mr. Richard A. Paulson M.B.A.
Employee
325
Address
85 Wells Avenue
Newton, 02459

Karyopharm Therapeutics Inc. Executives & BODs

Karyopharm Therapeutics Inc. Executives & BODs
# Name Age
1 Mr. James Accumanno J.D.
Chief Compliance Officer
70
2 Dr. Reshma Rangwala M.D., Ph.D.
Executive Vice President, Chief Medical Officer & Head of Research
70
3 Mr. Brendan Twohig Strong
SVice President of Investor Relations & Corporate Communications
70
4 Ms. Sohanya Cheng M.B.A.
Executive Vice President, Chief Commercial Officer & Head of Business Development
70
5 Ms. Kristin Abate
Vice President, Chief Accounting Officer, Interim Principal Financial Officer & Assistant Treasurer
70
6 Mr. Michael J. Mano J.D.
Senior Vice President, General Counsel & Secretary
70
7 Dr. Sharon Shacham M.B.A., Ph.D.
Co-Founder & Chairman of Scientific Advisory Board
70
8 Mr. Richard A. Paulson M.B.A.
President, Chief Executive Officer & Director
70
9 Mr. Stuart Poulton
Executive Vice President & Chief Development Officer
70
10 Dr. Mansoor Raza Mirza M.D.
Clinical Consultant, Member of Scientific Advisory Board & Independent Director
70

Karyopharm Therapeutics Inc. Competitors